Ikintu cya mbere kigira ingaruka ku gufata amazi muriHydroxypropyl methylcellulose(HPMC)ibicuruzwa ni urwego rwo gusimbuza (DS). DS bivuga umubare wa hydroxypropyl na methyl matsinda yometse kuri buri selile. Mubisanzwe, hejuru ya DS, nibyiza byo gufata amazi ya HPMC. Ni ukubera ko DS yiyongereye iganisha kumatsinda menshi ya hydrophilique kumugongo wa selile, bigatuma habaho imikoranire ikomeye na molekile zamazi hamwe nubushobozi bwo gufata amazi.
Ikindi kintu cyingenzi kigira ingaruka kumazi ni uburemere bwa HPMC. Uburemere bwa molekuline bugira ingaruka ku bwiza bwibisubizo bya HPMC, kandi polimeri iremereye ya polimeri isanzwe igaragaza uburyo bwiza bwo gufata amazi. Ingano nini yiyi polymers ikora imiterere yagutse y'urusobe, ikongerana na molekile y'amazi bityo bigatuma amazi agumana. Nyamara, ni ngombwa gushakisha uburinganire, kuko uburemere burenze urugero bwa molekile burashobora gutuma ubwiyongere bwiyongera kandi bukagabanuka kumurimo, bikagorana gufata cyangwa gukoresha ibicuruzwa bya HPMC mubisabwa bimwe.
Byongeye kandi, kwibumbira hamwe kwa HPMC muburyo bwo gukora nabyo bigira uruhare runini mu gufata amazi. Ubushuhe bwinshi bwa HPMC muri rusange buganisha ku gufata neza amazi. Ibi biterwa nuko kwibanda cyane byongera umubare wa hydrophilique iboneka kugirango amazi yinjizwe, bikavamo ubushobozi bwo gufata amazi. Nyamara, kwibanda cyane birashobora gutuma umuntu yiyongera cyane, bigatuma formulaire igorana kubyitwaramo no kuyishyira mubikorwa. Nibyingenzi gushakisha uburyo bwiza bwa HPMC bushingiye kubisabwa byihariye kugirango ugere kubintu bifuza kubika amazi utabangamiye imikorere yibicuruzwa.
Usibye ibi bintu byibanze, ibindi bintu bitandukanye birashobora guhindura imiterere yo gufata amazi yaHPMCibicuruzwa. Ubwoko nubunini bwinyongera zikoreshwa mugutegura birashobora kugira ingaruka zikomeye. Kurugero, kwongeramo plasitike cyangwa guhindura rheologiya birashobora kongera gufata amazi muguhindura imiterere ya HPMC no gukorana na molekile zamazi. Ibintu bidukikije nkubushyuhe nubushuhe birashobora no kugira ingaruka kumazi, kuko ibyo bipimo bigira ingaruka kumuvuduko wamazi no kwinjizwa. Imiterere ya substrate cyangwa hejuru yubutaka irashobora kurushaho kugira ingaruka kumazi, kuko itandukaniro mubyiza cyangwa hydrophilique bishobora kugira ingaruka kubushobozi bwa substrate yo gufata no kugumana amazi.
Ibikoresho byo kubika amazi yibicuruzwa bya HPMC biterwa nibintu bitandukanye, harimo urugero rwo gusimbuza, uburemere bwa molekile, kwibanda, inyongeramusaruro, ibintu bidukikije, hamwe nubutaka bwimiterere. Gusobanukirwa nibi bintu ni ngombwa muguteguraIbicuruzwa bishingiye kuri HPMCKuri Porogaramu zitandukanye. Muguhindura ibyo bintu, ababikora barashobora kongera imiterere yo gufata amazi ya HPMC kandi bakemeza ko ikora neza mubikorwa nka farumasi, ubwubatsi, no kwita kubantu. Ubundi bushakashatsi niterambere muriki gice bizakomeza kwagura imyumvire yacu yibintu bigira uruhare runini mu gufata amazi mu bicuruzwa bya HPMC kandi bizafasha iterambere ry’imikorere myiza kandi ikora neza.
Igihe cyo kohereza: Ugushyingo-02-2023